HOTAIR interacts with PRC2 complex regulating the regional preadipocyte transcriptome and human fat distribution
<p>Mechanisms governing regional human adipose tissue (AT) development remain undefined. Here, we show that the long non-coding RNA <em>HOTAIR</em> (HOX transcript antisense RNA) is exclusively expressed in gluteofemoral AT, where it is essential for adipocyte development. We find...
Asıl Yazarlar: | , , , , , , , , , , , , , , , , |
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Materyal Türü: | Journal article |
Dil: | English |
Baskı/Yayın Bilgisi: |
Cell Press
2022
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