What is the mechanism of action of anti-tumour necrosis factor-alpha antibody in rheumatoid arthritis?

The rationale for anti-tumour necrosis factor-alpha (anti-TNFalpha) therapy in rheumatoid arthritis (RA) is based on experiments on cultures of human rheumatoidjoint tissue, supported by experiments in animal models, all of which demonstrated that anti-TNFalpha antibody had profound effects on the d...

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Detalles Bibliográficos
Autor principal: Feldmann, M
Formato: Journal article
Lenguaje:English
Publicado: 1996