Cell entry mechanism of enzymatic bacterial colicins: porin recruitment and the thermodynamics of receptor binding.

Binding of enzymatic E colicins to the vitamin B12 receptor, BtuB, is the first stage in a cascade of events that culminate in the translocation of the cytotoxic nuclease into the Escherichia coli cytoplasm and release of its tightly bound immunity protein. A dogma of colicin biology is that the tox...

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Detalhes bibliográficos
Main Authors: Housden, N, Loftus, SR, Moore, G, James, R, Kleanthous, K
Formato: Journal article
Idioma:English
Publicado em: 2005