The role of Polo-like kinase 1 in the inhibition of centrosome separation after ionizing radiation.

Activation of the G2/M cell cycle checkpoint by DNA damage prevents cells from entering mitosis. Centrosome separation is initiated in G2 phase and completed in M phase. This critical process for cell division is targeted by G2/M checkpoint. Here we show that Plk1 signaling plays an important role i...

詳細記述

書誌詳細
主要な著者: Zhang, W, Fletcher, L, Muschel, R
フォーマット: Journal article
言語:English
出版事項: 2005