The role of Polo-like kinase 1 in the inhibition of centrosome separation after ionizing radiation.
Activation of the G2/M cell cycle checkpoint by DNA damage prevents cells from entering mitosis. Centrosome separation is initiated in G2 phase and completed in M phase. This critical process for cell division is targeted by G2/M checkpoint. Here we show that Plk1 signaling plays an important role i...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2005
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