Differential proteome analysis of TRAP-activated platelets: involvement of DOK-2 and phosphorylation of RGS proteins.

We have applied a proteomics approach to analyze signaling cascades in human platelets stimulated by thrombin receptor activating peptide (TRAP). By analyzing basal and TRAP-activated platelets using 2-dimensional gel electrophoresis (2-DE), we detected 62 differentially regulated protein features....

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Bibliographic Details
Main Authors: García, A, Prabhakar, S, Hughan, S, Anderson, T, Brock, C, Pearce, A, Dwek, R, Watson, S, Hebestreit, H, Zitzmann, N
Format: Journal article
Language:English
Published: American Society of Hematology 2004