Exocytosis elicited by action potentials and voltage-clamp calcium currents in individual mouse pancreatic B-cells.

1. Measurements of membrane capacitance, as an indicator of exocytosis, and intracellular Ca2+ concentration ([Ca2+]i) were used to determine the Ca2+ dependence of secretion in single pancreatic B-cells. 2. Exocytosis was dependent on a rise in [Ca2+]i and could be evoked by activation of voltage-d...

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Autors principals: Ammälä, C, Eliasson, L, Bokvist, K, Larsson, O, Ashcroft, F, Rorsman, P
Format: Journal article
Idioma:English
Publicat: 1993