CpG methylation profiling in VHL related and VHL unrelated renal cell carcinoma.

BACKGROUND: Renal cell carcinoma (RCC) is histopathologically heterogeneous with clear cell and papillary the most common subtypes. The most frequent molecular abnormality in clear cell RCC is VHL inactivation but promoter methylation of tumour suppressor genes is common in both subtypes of RCC. To...

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Bibliographic Details
Main Authors: McRonald, F, Morris, MR, Gentle, D, Winchester, L, Baban, D, Ragoussis, J, Clarke, N, Brown, MD, Kishida, T, Yao, M, Latif, F, Maher, E
Format: Journal article
Language:English
Published: 2009