Glycocalyx breakdown is associated with severe disease and fatal outcome in plasmodium falciparum Malaria

Background:Interactions between the endothelium and infected erythrocytes, microvascular dysfunction and parasite sequestration play major roles in the pathogenesis of severe falciparum malaria. The glycocalyx is a carbohydrate-rich layer lining the endothelium mediating NO production and vascular h...

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Bibliographic Details
Main Authors: Yeo, T, Weinberg, J, Lampah, D, Kenangalem, E, Bush, P, Chen, Y, Price, R, Young, S, Zhang, H, Millington, D, Granger, D, Anstey, N
Format: Journal article
Language:English
Published: Oxford University Press 2019