Control of experimental inflammatory bowel disease by regulatory T cells

A helper T cell type 1-mediated colitis driven by enteric bacteria develops in severe combined immunodeficient mice after transfer of CD45RB(high)CD4(+) T cells. Development of disease can be prevented by cotransfer of the reciprocal CD45RB(low) subset. Analysis of the mechanism of immune suppressio...

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Bibliographic Details
Main Authors: Asseman, C, Fowler, S, Powrie, F
Format: Conference item
Published: 2000