Control of experimental inflammatory bowel disease by regulatory T cells
A helper T cell type 1-mediated colitis driven by enteric bacteria develops in severe combined immunodeficient mice after transfer of CD45RB(high)CD4(+) T cells. Development of disease can be prevented by cotransfer of the reciprocal CD45RB(low) subset. Analysis of the mechanism of immune suppressio...
Main Authors: | , , |
---|---|
Format: | Conference item |
Published: |
2000
|