Unique T cell effector functions elicited by Plasmodium falciparum epitopes in malaria-exposed Africans tested by three T cell assays.

Natural immunity to malaria is characterized by low level CD4 T cell reactivity detected by either lymphoproliferation or IFN-gamma secretion. Here we show a doubling in the detection rate of responders to the carboxyl terminus of circumsporozoite protein (CS) of Plasmodium falciparum by employing t...

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Bibliographic Details
Main Authors: Flanagan, K, Lee, E, Gravenor, M, Reece, W, Urban, B, Doherty, T, Bojang, K, Pinder, M, Hill, A, Plebanski, M
Format: Journal article
Language:English
Published: 2001