The effects of mutational processes and selection on driver mutations across cancer types

Epidemiological evidence has long associated environmental mutagens with increased cancer risk. However, links between specific mutation-causing processes and the acquisition of individual driver mutations have remained obscure. Here we have used public cancer sequencing data from 11,336 cancers of...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Temko, D, Tomlinson, I, Severini, S, Schuster-Boeckler, P, Graham, T
التنسيق: Journal article
منشور في: Springer Nature 2018