Development of homogeneous luminescence assays for histone demethylase catalysis and binding.

Covalent modifications to histones play important roles in chromatin dynamics and the regulation of gene expression. The JumonjiC (JmjC)-containing histone demethylases (HDMs) catalyze the demethylation of methylated lysine residues on histone tails. Here we report the development of homogeneous lum...

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Detaylı Bibliyografya
Asıl Yazarlar: Kawamura, A, Tumber, A, Rose, N, King, O, Daniel, M, Oppermann, U, Heightman, T, Schofield, C
Materyal Türü: Journal article
Dil:English
Baskı/Yayın Bilgisi: 2010
Konular: