Biological properties of influenza A virus mutants with amino acid substitutions in the HA2 glycoprotein of the HA1/HA2 interaction region

Influenza A viruses (IAVs) enter into cells by receptor-dependent endocytosis. Subsequently, conformational changes of haemagglutinin are triggered by low environmental pH and the N terminus of HA2 glycoprotein (gp) is inserted into the endosomal membrane, resulting in fusion pore formation and geno...

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Bibliographic Details
Main Authors: Jakubcová, L, Vozárová, M, Hollý, J, Tomčíková, K, Fogelová, M, Polčicová, K, Kostolanský, F, Fodor, E, Varečková, E
Format: Journal article
Published: Microbiology Society 2019