Shigella flexneri Spa15 crystal structure verified in solution by double electron electron resonance.

Shigella flexneri Spa15 is a chaperone of the type 3 secretion system, which binds a number of effectors to ensure their stabilization prior to secretion. One of these effectors is IpgB1, a mimic of the human Ras-like Rho guanosine triphosphatase RhoG. In this study, Spa15 alone and in complex with...

Full description

Bibliographic Details
Main Authors: Lillington, J, Lovett, J, Johnson, S, Roversi, P, Timmel, C, Lea, S
Format: Journal article
Language:English
Published: 2011