The ubiquitin-proteasome pathway in cancer.

Degradation by the 26S proteasome of specific proteins that have been targeted by the ubiquitin pathway is the major intracellular non-lysosomal proteolytic mechanism and is involved in a broad range of processes, such as cell cycle progression, antigen presentation and control of gene expression. R...

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Bibliographic Details
Main Authors: Spataro, V, Norbury, C, Harris, A
Format: Journal article
Language:English
Published: 1998