The ubiquitin-proteasome pathway in cancer.
Degradation by the 26S proteasome of specific proteins that have been targeted by the ubiquitin pathway is the major intracellular non-lysosomal proteolytic mechanism and is involved in a broad range of processes, such as cell cycle progression, antigen presentation and control of gene expression. R...
Main Authors: | Spataro, V, Norbury, C, Harris, A |
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Format: | Journal article |
Language: | English |
Published: |
1998
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