Modification of the histone landscape with JAK inhibition in myeloproliferative neoplasms

Dysregulation of epigenetic processes is increasingly understood to play a role in the pathogenesis of myeloproliferative neoplasms (MPNs). Ruxolitinib, a JAK/STAT inhibitor, has proved a useful addition to the therapeutic arsenal for these disorders, but has limited disease modifying activity. We d...

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التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Greenfield, G, McPherson, S, Smith, J, Mead, A, Harrison, C, Mills, K, McMullin, MF
التنسيق: Journal article
اللغة:English
منشور في: MDPI 2020