Inhibition of JMJD6 by 2-oxoglutarate mimics
Studies on the inhibition of the human 2-oxoglutarate dependent oxygenase JMJD6, which is a cancer target, by 2-oxoglutarate mimics / competitors, including human drugs, drug candidates, and metabolites relevant to cancer are described. JMJD6 assays employed NMR to monitor inhibitor binding and use...
Main Authors: | , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
Chemistry Europe
2021
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