Myelodysplastic syndromes are propagated by rare and distinct human cancer stem cells in vivo.

Myelodysplastic syndromes are propagated by rare and distinct human cancer stem cells in vivo.

Diğer sürümleri göster (1)

Evidence for distinct human cancer stem cells (CSCs) remains contentious and the degree to which different cancer cells contribute to propagating malignancies in patients remains unexplored. In low- to intermediate-risk myelodysplastic syndromes (MDS), we establish the existence of rare multipotent...

Detaylı Bibliyografya
Asıl Yazarlar:	Woll, P, Kjällquist, U, Chowdhury, O, Doolittle, H, Wedge, D, Thongjuea, S, Erlandsson, R, Ngara, M, Anderson, K, Deng, Q, Mead, A, Stenson, L, Giustacchini, A, Duarte, S, Giannoulatou, E, Taylor, S, Karimi, M, Scharenberg, C, Mortera-Blanco, T, Macaulay, I, Clark, SA, Dybedal, I, Josefsen, D, Fenaux, P, Hokland, P, Holm, MS, Cazzola, M, Malcovati, L, Tauro, S, Bowen, D, Boultwood, J, Pellagatti, A, Pimanda, J, Unnikrishnan, A, Vyas, P, Göhring, G, Schlegelberger, B, Tobiasson, M, Kvalheim, G, Constantinescu, SN, Nerlov, C, Nilsson, L, Campbell, P, Sandberg, R, Papaemmanuil, E, Hellström-Lindberg, E, Linnarsson, S, Jacobsen, S
Materyal Türü:	Journal article
Dil:	English
Baskı/Yayın Bilgisi:	Cell Press 2014

Benzer Materyaller

Erratum to Myelodysplastic syndromes are propagated by rare and distinct human cancer stem cells in vivo [Cancer Cell, 25 (2014) 794-808]
Yazar:: Woll, P, ve diğerleri
Baskı/Yayın Bilgisi: (2014)

Myelodysplastic syndromes are propagated by rare and distinct human cancer stem cells in vivo
Yazar:: Woll, P, ve diğerleri
Baskı/Yayın Bilgisi: (2014)

A dynamic niche provides Kit ligand in a stage-specific manner to the earliest thymocyte progenitors
Yazar:: Buono, M, ve diğerleri
Baskı/Yayın Bilgisi: (2015)

Perturbed hematopoietic stem and progenitor cell hierarchy in myelodysplastic syndromes patients with monosomy 7 as the sole cytogenetic abnormality.
Yazar:: Dimitriou, M, ve diğerleri
Baskı/Yayın Bilgisi: (2016)

Distinct myeloid progenitor differentiation pathways identified through single cell RNA sequencing
Yazar:: Drissen, R, ve diğerleri
Baskı/Yayın Bilgisi: (2016)

Single cell RNA sequencing reveals molecular and functional platelet bias of aged hematopoietic stem cells
Yazar:: Nerlov, C, ve diğerleri
Baskı/Yayın Bilgisi: (2016)

The transporter ABCB7 is a mediator of the phenotype of acquired refractory anemia with ring sideroblasts
Yazar:: Nikpour, M, ve diğerleri
Baskı/Yayın Bilgisi: (2013)

THIRD GENERATION AUTOLOGOUS MYELOID-DERIVED DENDRITIC CELLS DEVELOPED FROM PATIENTS WITH CMML AND MDS DEMONSTRATE PHENOTYPIC PROPERTIES OF MATURE FUNCTIONAL DENDRITIC CELLS
Yazar:: Anderson, K, ve diğerleri
Baskı/Yayın Bilgisi: (2014)

Identification of two distinct pathways of human myelopoiesis
Yazar:: Drissen, R, ve diğerleri
Baskı/Yayın Bilgisi: (2019)

Board Structure, Mergers and Shareholder Wealth: A Study of the Mutual Fund Industry
Yazar:: Tufano, P, ve diğerleri
Baskı/Yayın Bilgisi: (2007)

Board structure, mergers, and shareholder wealth: a study of the mutual fund industry
Yazar:: Tufano, P, ve diğerleri
Baskı/Yayın Bilgisi: (2004)

The transporter ABCB7 is a mediator of the phenotype of acquired refractory anemia with ring sideroblasts.
Yazar:: Nikpour, M, ve diğerleri
Baskı/Yayın Bilgisi: (2013)

Clonal heterogeneity in the 5q- syndrome: p53 expressing progenitors prevail during lenalidomide treatment and expand at disease progression.
Yazar:: Jädersten, M, ve diğerleri
Baskı/Yayın Bilgisi: (2009)

SPECTRUM OF CLINICAL PHENOTYPES AND SOMATIC VARIANTS IN RUNX1-ASSOCIATED FAMILIAL PLATELET DISORDER WITH PREDISPOSITION TO HEMATOLOGIC MALIGNANCIES
Yazar:: Alisa Förster, ve diğerleri
Baskı/Yayın Bilgisi: (2023-12-01)

Niche-mediated depletion of the normal hematopoietic stem cell reservoir by Flt3-ITD–induced myeloproliferation
Yazar:: Mead, A, ve diğerleri
Baskı/Yayın Bilgisi: (2017)

COMPREHENSIVE ANALYSIS OF MUTATION STATUS, GENE EXPRESSION PROFILES, BLOOD AND BONE MARROW COUNTS AND OUTCOME IN PATIENTS WITH MYELODYSPLASTIC SYNDROMES
Yazar:: Pellagatti, A, ve diğerleri
Baskı/Yayın Bilgisi: (2014)

Exome sequencing of primary breast cancers with paired metastatic lesions reveals metastasis-enriched mutations in the A-kinase anchoring protein family (AKAPs)
Yazar:: Una Kjällquist, ve diğerleri
Baskı/Yayın Bilgisi: (2018-02-01)

Clinical and biological implications of driver mutations in myelodysplastic syndromes.
Yazar:: Papaemmanuil, E, ve diğerleri
Baskı/Yayın Bilgisi: (2013)

Hematopoietic stem cell heterogeneity and age-associated platelet bias are evolutionarily conserved
Yazar:: Aksöz, M, ve diğerleri
Baskı/Yayın Bilgisi: (2024)

Single-cell RNA sequencing reveals molecular and functional platelet bias of aged haematopoietic stem cells
Yazar:: Amit Grover, ve diğerleri
Baskı/Yayın Bilgisi: (2016-03-01)

High Throughput Targeted Gene Sequencing in 738 Myelodysplastic Syndromes Patients Reveals Novel Oncogenic Genes, Rare Driver Mutations and Complex Molecular Signatures with Potential Impact for Patient Diagnosis and Prognosis in the Clinic
Yazar:: Papaemmanuil, E, ve diğerleri
Baskı/Yayın Bilgisi: (2012)

Initial seeding of the embryonic thymus by immune-restricted lympho-myeloid progenitors
Yazar:: Luis, T, ve diğerleri
Baskı/Yayın Bilgisi: (2016)

Sodium diffusion in 4H-SiC
Yazar:: M. K. Linnarsson, ve diğerleri
Baskı/Yayın Bilgisi: (2014-09-01)

Single-cell transcriptomics uncovers distinct molecular signatures of stem cells in chronic myeloid leukemia
Yazar:: Giustacchini, A, ve diğerleri
Baskı/Yayın Bilgisi: (2017)

Estimating mutation rates from paternity casework.
Yazar:: Vicard, P, ve diğerleri
Baskı/Yayın Bilgisi: (2008)

Dynamics of Transforming Growth Factor (TGF)-β superfamily cytokine induction during HIV-1 infection are distinct from other innate cytokines
Yazar:: Dickinson, M, ve diğerleri
Baskı/Yayın Bilgisi: (2020)

C/EBPα and GATA-2 mutations induce bilineage acute erythroid leukemia through transformation of a neomorphic neutrophil-erythroid progenitor
Yazar:: Di Genua, C, ve diğerleri
Baskı/Yayın Bilgisi: (2020)

GFI1(36N) as a therapeutic and prognostic marker for myelodysplastic syndrome (MDS)
Yazar:: Botezatu, L, ve diğerleri
Baskı/Yayın Bilgisi: (2016)

Identification of aberrant splicing events in myelodysplastic syndrome patients with splicing factor gene mutations
Yazar:: Pellagatti, A, ve diğerleri
Baskı/Yayın Bilgisi: (2017)

CRISPR-Cas9-induced t(11;19)/MLL-ENL translocations initiate leukemia in human hematopoietic progenitor cells in vivo
Yazar:: Jana Reimer, ve diğerleri
Baskı/Yayın Bilgisi: (2017-09-01)

Studying BDNF/TrkB Signaling: Transcriptome Analysis from a Limited Number of Purified Adult or Aged Murine Brain Neurons
Yazar:: Vatanashevanopakorn, C, ve diğerleri
Baskı/Yayın Bilgisi: (2017)

GABP is necessary for stem/progenitor cell maintenance and myeloid differentiation in human hematopoiesis and chronic myeloid leukemia
Yazar:: Georgi Manukjan, ve diğerleri
Baskı/Yayın Bilgisi: (2016-05-01)

Somatic SF3B1 mutation in myelodysplasia with ring sideroblasts.
Yazar:: Papaemmanuil, E, ve diğerleri
Baskı/Yayın Bilgisi: (2011)

Next generation sequencing techniques reveal molecular mechanisms of MYB regulation and function in MLL-AF9 Leukemia
Yazar:: Lau, I, ve diğerleri
Baskı/Yayın Bilgisi: (2017)

271 Consistent high-quality dendritic cell vaccines produced post-chemotherapy in patients with acute myeloid leukemia for use in a Phase I/II trial
Yazar:: Gunnar Kvalheim, ve diğerleri
Baskı/Yayın Bilgisi: (2020-11-01)

Caring for preservation - coring for prehistoric life. Revisiting 15 000 years of sedimentation at the Ageröd peatland, Southern Sweden
Yazar:: Anton Hansson, ve diğerleri
Baskı/Yayın Bilgisi: (2024-12-01)

Clinical significance of SF3B1 mutations in myelodysplastic syndromes and myelodysplastic/myeloproliferative neoplasms.
Yazar:: Malcovati, L, ve diğerleri
Baskı/Yayın Bilgisi: (2011)

Platelet-biased stem cells reside at the apex of the haematopoietic stem-cell hierarchy
Yazar:: Sanjuan-Pla, A, ve diğerleri
Baskı/Yayın Bilgisi: (2013)

“Hearken to the Hermit-Thrush”1: A Case Study in Interdisciplinary Listening
Yazar:: Emily L. Doolittle
Baskı/Yayın Bilgisi: (2020-12-01)

Principles of reconstructing the subclonal architecture of cancers
Yazar:: Dentro, S, ve diğerleri
Baskı/Yayın Bilgisi: (2017)