Low-dose growth hormone inhibits 11 beta-hydroxysteroid dehydrogenase type 1 but has no effect upon fat mass in patients with simple obesity.

GH has potent effects on adipocyte biology, stimulating lipolysis but also promoting preadipocyte proliferation. In addition, GH, acting through IGF-I, inhibits 11 beta-hydroxysteroid dehydrogenase type 1 (11 beta-HSD1), which converts the inactive glucocorticoid, cortisone (E), to active cortisol (...

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Xehetasun bibliografikoak
Egile Nagusiak: Tomlinson, J, Crabtree, N, Clark, P, Holder, G, Toogood, A, Shackleton, C, Stewart, P
Formatua: Journal article
Hizkuntza:English
Argitaratua: 2003

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