Enhanced H-bonding and pi-stacking in DNA: a potent duplex-stabilizing and mismatch sensing nucleobase analogue
X-pyrene is a new nucleic acid duplex stabilizing cytosine analogue that combines enhanced π-stacking, hydrogen bonding and electrostatic interactions to greatly increase the stability of bulged DNA duplexes and DNA/RNA hybrids. X-pyrene is highly selective for guanine as a partner and duplex stabil...
Asıl Yazarlar: | , , , , |
---|---|
Materyal Türü: | Journal article |
Baskı/Yayın Bilgisi: |
Royal Society of Chemistry
2014
|