Elevating high-density lipoprotein cholesterol in apolipoprotein E-deficient mice remodels advanced atherosclerotic lesions by decreasing macrophage and increasing smooth muscle cell content.

BACKGROUND: HDL cholesterol levels are inversely correlated with coronary heart disease risk in humans, and in animal studies, HDL elevation decreases formation and progression of foam-cell lesions. The potential for HDL to affect preexisting advanced atherosclerotic lesions is not known. To approac...

全面介紹

書目詳細資料
Main Authors: Rong, J, Li, J, Reis, E, Choudhury, R, Dansky, H, Elmalem, V, Fallon, J, Breslow, J, Fisher, E
格式: Journal article
語言:English
出版: 2001