Altered peptide ligands trigger perforin- rather than Fas-dependent cell lysis.

Altered peptide ligands trigger perforin- rather than Fas-dependent cell lysis.

CTLs lyse Fas-expressing target cells by the concomitant action of a perforin- and a Fas-dependent mechanism. This study analyzed whether target cells pulsed with T cell antagonists and other altered peptide ligands (APLs) were susceptible selectively to only one of these two mechanisms. In vivo and...

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Dettagli Bibliografici
Autori principali:	Bachmann, M, Ohteki, T, Faienza, K, Zakarian, A, Kägi, D, Speiser, D, Ohashi, P
Natura:	Journal article
Lingua:	English
Pubblicazione:	1997

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