Distal and proximal hypoxia response elements cooperate to regulate organ-specific erythropoietin gene expression
While it is well-established that distal hypoxia response elements (HREs) regulate hypoxia-inducible factor (HIF) target genes such as erythropoietin (Epo), an interplay between multiple distal and proximal (promoter) HREs has not been described so far. Hepatic Epo expression is regulated by a HRE l...
| Autori principali: | , , , , , , , , , |
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| Natura: | Journal article |
| Lingua: | English |
| Pubblicazione: |
Ferrata Storti Foundation
2019
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