The 3' untranslated region of tumor necrosis factor alpha mRNA is a target of the mRNA-stabilizing factor HuR.

Posttranscriptional regulation is important for tumor necrosis factor alpha (TNF-alpha) expression in monocytes and macrophages, and an AU-rich element (ARE) in the 3' untranslated region (UTR) of TNF-alpha mRNA is implicated in control of its translation and mRNA stability. Regulation of mRNA...

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Bibliographic Details
Main Authors: Dean, J, Wait, R, Mahtani, K, Sully, G, Clark, A, Saklatvala, J
Format: Journal article
Language:English
Published: 2001