Re-purposing Ac/Ds transgenic system for CRISPR/dCas9 modulation of enhancers and non-coding RNAs in zebrafish

Due to its genetic amenability coupled with recent advances in genome editing, the zebrafish serves as an excellent model to examine the function of both coding and non-coding elements. Recently, the non-coding genome has gained prominence due to its critical role in development and disease. Here, w...

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Bibliographic Details
Main Authors: Chong-Morrison, V, Simoes, F, Senanayake, U, Carroll, D, Riley, P, Sauka-Spengler, T
Format: Working paper
Published: 2018