A very stable cyclic DNA miniduplex with just two base pairs.

(Chemical Equation Presented) What goes around... Cyclic mini-DNA duplexes, as shown in the scheme, have been synthesized in high yield on the multimicromole scale by using click chemistry. These B-like duplexes are very stable and bind to drugs, such as distamycin A and 7-aminoactinomycin D. Circul...

Полное описание

Библиографические подробности
Главные авторы: El-Sagheer, A, Kumar, R, Findlow, S, Werner, J, Lane, A, Brown, T
Формат: Journal article
Язык:English
Опубликовано: 2008