MTHFR 677 C>T Polymorphism reveals functional importance for 5-methyltetrahydrofolate, not homocysteine, in regulation of vascular redox state and endothelial function in human atherosclerosis.

BACKGROUND: The role of circulating homocysteine as an atherosclerosis risk factor has recently been questioned. However, 5-methyl-tetrahydrofolate (5-MTHF), the circulating metabolite of folic acid participating in homocysteine metabolism, has direct effects on vascular function. We sought to dist...

Mô tả đầy đủ

Chi tiết về thư mục
Những tác giả chính: Antoniades, C, Shirodaria, C, Leeson, P, Baarholm, O, Van-Assche, T, Cunnington, C, Pillai, R, Ratnatunga, C, Tousoulis, D, Stefanadis, C, Refsum, H, Channon, K
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: 2009