MTHFR 677 C>T Polymorphism reveals functional importance for 5-methyltetrahydrofolate, not homocysteine, in regulation of vascular redox state and endothelial function in human atherosclerosis.

MTHFR 677 C>T Polymorphism reveals functional importance for 5-methyltetrahydrofolate, not homocysteine, in regulation of vascular redox state and endothelial function in human atherosclerosis.

BACKGROUND: The role of circulating homocysteine as an atherosclerosis risk factor has recently been questioned. However, 5-methyl-tetrahydrofolate (5-MTHF), the circulating metabolite of folic acid participating in homocysteine metabolism, has direct effects on vascular function. We sought to dist...

Bibliográfalaš dieđut
Váldodahkkit:	Antoniades, C, Shirodaria, C, Leeson, P, Baarholm, O, Van-Assche, T, Cunnington, C, Pillai, R, Ratnatunga, C, Tousoulis, D, Stefanadis, C, Refsum, H, Channon, K
Materiálatiipa:	Journal article
Giella:	English
Almmustuhtton:	2009

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