The loss of ATRX increases susceptibility to pancreatic injury and oncogenic KRAS in female but not male mice
<strong>Background</strong> Pancreatic ductal adenocarcinoma (PDAC) is the third leading cause of cancer death in North America, accounting for >30,000 deaths annually. Although somatic activating mutations in KRAS appear in 97% of PDAC patients, additional factors are required to...
| Հիմնական հեղինակներ: | , , , , , , , , , |
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| Ձևաչափ: | Journal article |
| Հրապարակվել է: |
Elsevier
2018
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