The loss of ATRX increases susceptibility to pancreatic injury and oncogenic KRAS in female but not male mice

The loss of ATRX increases susceptibility to pancreatic injury and oncogenic KRAS in female but not male mice

<strong>Background</strong> Pancreatic ductal adenocarcinoma (PDAC) is the third leading cause of cancer death in North America, accounting for >30,000 deaths annually. Although somatic activating mutations in KRAS appear in 97% of PDAC patients, additional factors are required to...

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Bibliographic Details
Main Authors:	Young, C, Baker, R, Howlett, C, Hryciw, T, Herman, J, Higgs, D, Gibbons, R, Crawford, H, Brown, A, Pin, C
Format:	Journal article
Published:	Elsevier 2018

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