Overexpression of lymphotoxin in T cells induces fulminant thymic involution.
Activated lymphocytes and lymphoid-tissue inducer cells express lymphotoxins (LTs), which are essential for the organogenesis and maintenance of lymphoreticular microenvironments. Here we describe that T-cell-restricted overexpression of LT induces fulminant thymic involution. This phenotype was pre...
Prif Awduron: | Heikenwalder, M, Prinz, M, Zeller, N, Lang, K, Junt, T, Rossi, S, Tumanov, A, Schmidt, H, Priller, J, Flatz, L, Rülicke, T, Macpherson, A, Holländer, G, Nedospasov, SA, Aguzzi, A |
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Fformat: | Journal article |
Iaith: | English |
Cyhoeddwyd: |
2008
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Eitemau Tebyg
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