Genome-wide allelotyping of 104 Finnish colorectal cancers reveals an excess of allelic imbalance in chromosome 20q in familial cases.

We have allelotyped a series of 104 Finnish colorectal cancers (CRCs) using 372 polymorphic markers spaced, on average, at 10 cM intervals, and have made a comparison of the differences in the frequency of allelic imbalance (AI) between familial and sporadic cases. Differences in the frequency of al...

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Bibliographic Details
Main Authors: Laiho, P, Hienonen, T, Karhu, A, Lipton, L, Aalto, Y, Thomas, H, Birkenkamp-Demtroder, K, Hodgson, S, Salovaara, R, Mecklin, J, Järvinen, H, Knuutila, S, Halford, S, Ørntoft, T, Tomlinson, I, Launonen, V, Houlston, R, Aaltonen, L
Format: Journal article
Language:English
Published: 2003