Relationships between the N-glycan structures and biological activities of recombinant human erythropoietins produced using different culture conditions and purification procedures.

Eight preparations of recombinant human erythropoietin (EPO) with differing isoform compositions were produced by using different culture conditions and purification procedures. The N-glycan structures of these EPOs were analysed using a recently developed profiling procedure and identified using ma...

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Detalhes bibliográficos
Principais autores: Yuen, C, Storring, P, Tiplady, R, Izquierdo, M, Wait, R, Gee, C, Gerson, P, Lloyd, P, Cremata, J
Formato: Journal article
Idioma:English
Publicado em: 2003