Multiple colorectal adenomas, classic adenomatous polyposis, and germ-line mutations in MYH.
BACKGROUND: Germ-line mutations in the base-excision-repair gene MYH have been associated with recessive inheritance of multiple colorectal adenomas. Tumors from affected persons displayed excess somatic transversions of a guanine-cytosine pair to a thymine-adenine pair (G:C-->T:A) in the AP...
Päätekijät: | , , , , , , , , , , , |
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Aineistotyyppi: | Journal article |
Kieli: | English |
Julkaistu: |
2003
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