Multiple colorectal adenomas, classic adenomatous polyposis, and germ-line mutations in MYH.
BACKGROUND: Germ-line mutations in the base-excision-repair gene MYH have been associated with recessive inheritance of multiple colorectal adenomas. Tumors from affected persons displayed excess somatic transversions of a guanine-cytosine pair to a thymine-adenine pair (G:C-->T:A) in the AP...
المؤلفون الرئيسيون: | Sieber, O, Lipton, L, Crabtree, M, Heinimann, K, Fidalgo, P, Phillips, R, Bisgaard, M, Orntoft, T, Aaltonen, L, Hodgson, S, Thomas, H, Tomlinson, I |
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التنسيق: | Journal article |
اللغة: | English |
منشور في: |
2003
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مواد مشابهة
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Whole-gene APC deletions cause classical familial adenomatous polyposis, but not attenuated polyposis or "multiple" colorectal adenomas
حسب: Sieber, O, وآخرون
منشور في: (2002) -
Whole-gene APC deletions cause classical familial adenomatous polyposis, but not attenuated polyposis or "multiple" colorectal adenomas.
حسب: Sieber, O, وآخرون
منشور في: (2002) -
Carcinogenesis in MYH-associated polyposis follows a distinct genetic pathway.
حسب: Lipton, L, وآخرون
منشور في: (2003) -
Explaining differences in the severity of familial adenomatous polyposis and the search for modifier genes.
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منشور في: (2001) -
Explaining variation in familial adenomatous polyposis: relationship between genotype and phenotype and evidence for modifier genes.
حسب: Crabtree, MD, وآخرون
منشور في: (2002)