Multiple colorectal adenomas, classic adenomatous polyposis, and germ-line mutations in MYH.

Multiple colorectal adenomas, classic adenomatous polyposis, and germ-line mutations in MYH.

BACKGROUND: Germ-line mutations in the base-excision-repair gene MYH have been associated with recessive inheritance of multiple colorectal adenomas. Tumors from affected persons displayed excess somatic transversions of a guanine-cytosine pair to a thymine-adenine pair (G:C-->T:A) in the AP...

Podrobná bibliografie
Hlavní autoři:	Sieber, O, Lipton, L, Crabtree, M, Heinimann, K, Fidalgo, P, Phillips, R, Bisgaard, M, Orntoft, T, Aaltonen, L, Hodgson, S, Thomas, H, Tomlinson, I
Médium:	Journal article
Jazyk:	English
Vydáno:	2003

Podobné jednotky

Whole-gene APC deletions cause classical familial adenomatous polyposis, but not attenuated polyposis or "multiple" colorectal adenomas
Autor: Sieber, O, a další
Vydáno: (2002)

Whole-gene APC deletions cause classical familial adenomatous polyposis, but not attenuated polyposis or "multiple" colorectal adenomas.
Autor: Sieber, O, a další
Vydáno: (2002)

Carcinogenesis in MYH-associated polyposis follows a distinct genetic pathway.
Autor: Lipton, L, a další
Vydáno: (2003)

Explaining differences in the severity of familial adenomatous polyposis and the search for modifier genes.
Autor: Houlston, R, a další
Vydáno: (2001)

Explaining variation in familial adenomatous polyposis: relationship between genotype and phenotype and evidence for modifier genes.
Autor: Crabtree, MD, a další
Vydáno: (2002)

The role of cell proliferation and crypt fission in adenoma aggressiveness: a comparison of ileoanal pouch and rectal adenomas in familial adenomatous polyposis.
Autor: Will, O, a další
Vydáno: (2011)

The multiple colorectal adenoma phenotype and MYH, a base excision repair gene.
Autor: Lipton, L, a další
Vydáno: (2004)

Attenuated familial adenomatous polyposis: results from an international collaborative study.
Autor: Knudsen, A, a další
Vydáno: (2010)

Analysis of candidate modifier loci for the severity of colonic familial adenomatous polyposis, with evidence for the importance of the N-acetyl transferases.
Autor: Crabtree, MD, a další
Vydáno: (2004)

The adenomatous polyposis coli (APC) tumour suppressor--genetics, function and disease.
Autor: Sieber, O, a další
Vydáno: (2000)

Progression of duodenal neoplasia to advanced adenoma in patients with familial adenomatous polyposis
Autor: Hiroko Nakahira, a další
Vydáno: (2023-11-01)

Gene Expression Profiling in Familial Adenomatous Polyposis Adenomas and Desmoid Disease
Autor: Bowden Nikola A, a další
Vydáno: (2007-06-01)

Familial adenomatous polyposis
Autor: Rozen Paul, a další
Vydáno: (2009-10-01)

Expression Profiling of Proliferation and Apoptotic Markers along the Adenoma-Carcinoma Sequence in Familial Adenomatous Polyposis Patients
Autor: Wang, J, a další
Vydáno: (2013)

Endoscopic Approach to Duodenal Adenomas in Familial Adenomatous Polyposis: A Retrospective Cohort
Autor: Joana Lemos Garcia, a další
Vydáno: (2022-11-01)

Expression Profiling of Proliferation and Apoptotic Markers along the Adenoma-Carcinoma Sequence in Familial Adenomatous Polyposis Patients
Autor: Jayson Wang, a další
Vydáno: (2013-01-01)

The in vivo rate of somatic adenomatous polyposis coli mutation.
Autor: Hornsby, C, a další
Vydáno: (2008)

Mutation cluster region, association between germline and somatic mutations and genotype-phenotype correlation in upper gastrointestinal familial adenomatous polyposis.
Autor: Groves, C, a další
Vydáno: (2002)

Hepatocellular Carcinoma in the Adolescent With Classical Familial Adenomatous Polyposis: Clinical Case
Autor: Svetlana Ya. Volgina, a další
Vydáno: (2020-09-01)

Multiple Adenomatous Duodenal Polyposis
Autor: Zdena Zádorová, a další
Vydáno: (2013-01-01)

Familial adenomatous polyposis coli
Autor: K Boeren, a další
Vydáno: (2011-03-01)

Surveillance of duodenal adenomas in familial adenomatous polyposis patients: medical objectives and technical requirements
Autor: Jean-Christophe Saurin, a další
Vydáno: (2015-10-01)

Familial Adenomatous Polyposis (FAP) and Other Polyposis Syndromes
Autor: Scott Rodney J
Vydáno: (2003-12-01)

Controlling the disease in MYH-associated polyposis
Autor: LaGuardia Lisa, a další
Vydáno: (2011-03-01)

Variability in the severity of colonic disease in familial adenomatous polyposis results from differences in tumour initiation rather than progression and depends relatively little on patient age.
Autor: Crabtree, MD, a další
Vydáno: (2001)

Importance of Gastroduodenal Endoscopic Findings in Patients with Classic Familial Adenomatous Polyposis Syndrome
Autor: Seyed Reza Fatemi, a další
Vydáno: (2022-08-01)

Porcine familial adenomatous polyposis model enables systematic analysis of early events in adenoma progression
Autor: Tatiana Flisikowska, a další
Vydáno: (2017-07-01)

Expression of the Phosphorylated ERK and MEK MAPKs and Upstream Growth Factor Receptors in Adenomas and Carcinomas of Patients with Familial Adenomatous Polyposis
Autor: Hollingshead, J, a další
Vydáno: (2011)

Vaccines for cancer interception in familial adenomatous polyposis
Autor: David E. Johnson, a další
Vydáno: (2025-01-01)

Germline mutations but not somatic changes at the MYH locus contribute to the pathogenesis of unselected colorectal cancers.
Autor: Halford, SE, a další
Vydáno: (2003)

Familial adenomatous polyposis and desmoid tumors
Autor: Ana Elisa Moraes Righetti, a další
Vydáno: (2011-01-01)

Familial adenomatous polyposis and the small bowel: a loco-regional review and current management strategies.
Autor: Will, O, a další
Vydáno: (2008)

A comparison of the phenotype and genotype in adenomatous polyposis patients with and without a family history.
Autor: Truta, B, a další
Vydáno: (2005)

The clonal origin of human tumours: is familial adenomatous polyposis (FAP) different?
Autor: Leedham, S, a další
Vydáno: (2006)

Disease severity and genetic pathways in attenuated familial adenomatous polyposis vary greatly but depend on the site of the germline mutation.
Autor: Sieber, O, a další
Vydáno: (2006)

Investigation of pathogenic mechanisms in multiple colorectal adenoma patients without germline APC or MYH/MUTYH mutations.
Autor: Thirlwell, C, a další
Vydáno: (2007)

Familial Adenomatous Polyposis and Crohn's Disease in One Patient: Dilemmas and Concerns
Autor: Catarina Fidalgo, a další
Vydáno: (2013-08-01)

Surgical complications and metachronous rectal cancer risk in patients with classic familial adenomatous polyposis
Autor: Paulo Roberto Stevanato Filho, a další
Vydáno: (2015-01-01)

Cold snare polypectomy for duodenal adenomas in familial adenomatous polyposis: a prospective international cohort study
Autor: Arthur S. Aelvoet, a další
Vydáno: (2023-11-01)

Dye chromoendoscopy leads to a higher adenoma detection in the duodenum and stomach in patients with familial adenomatous polyposis
Autor: R. Hüneburg, a další
Vydáno: (2020-09-01)