Multiple colorectal adenomas, classic adenomatous polyposis, and germ-line mutations in MYH.

BACKGROUND: Germ-line mutations in the base-excision-repair gene MYH have been associated with recessive inheritance of multiple colorectal adenomas. Tumors from affected persons displayed excess somatic transversions of a guanine-cytosine pair to a thymine-adenine pair (G:C-->T:A) in the AP...

সম্পূর্ণ বিবরণ

গ্রন্থ-পঞ্জীর বিবরন
প্রধান লেখক: Sieber, O, Lipton, L, Crabtree, M, Heinimann, K, Fidalgo, P, Phillips, R, Bisgaard, M, Orntoft, T, Aaltonen, L, Hodgson, S, Thomas, H, Tomlinson, I
বিন্যাস: Journal article
ভাষা:English
প্রকাশিত: 2003