Inclusion of PF68 surfactant improves stability of rAAV titer when passed through a surgical device used in retinal gene therapy

Recent advances in recombinant adeno-associated virus (rAAV) gene therapy for choroideremia show gene replacement to be a promising approach. It is, however, well known that contact of vector solution with plastic materials in the surgical device may result in non-specific adsorption with resulting...

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Bibliographic Details
Main Authors: Patrício, M, Cox, C, Blue, C, Barnard, A, Martinez-Fernandez De La Camara, C, Maclaren, R
Format: Journal article
Language:English
Published: Cell Press 2019