The cardiac sympathetic co-transmitter galanin reduces acetylcholine release and vagal bradycardia: implications for neural control of cardiac excitability.

The autonomic phenotype of congestive cardiac failure is characterised by high sympathetic drive and impaired vagal tone, which are independent predictors of mortality. We hypothesize that impaired bradycardia to peripheral vagal stimulation following high-level sympathetic drive is due to sympatho-...

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Bibliographic Details
Main Authors: Herring, N, Cranley, J, Lokale, M, Li, D, Shanks, J, Alston, E, Girard, B, Carter, E, Parsons, R, Habecker, B, Paterson, D
Format: Journal article
Language:English
Published: Elsevier 2012