Organelle selection determines agonist-specific Ca2+ signals in pancreatic acinar and beta cells.

How different extracellular stimuli can evoke different spatiotemporal Ca2+ signals is uncertain. We have elucidated a novel paradigm whereby different agonists use different Ca2+-storing organelles ("organelle selection") to evoke unique responses. Some agonists select the endoplasmic ret...

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Bibliographic Details
Main Authors: Yamasaki, M, Masgrau, R, Morgan, A, Churchill, G, Patel, S, Ashcroft, S, Galione, A
Format: Journal article
Language:English
Published: 2004