Absolute quantitation of disease protein biomarkers in a single LC-MS acquisition using apolipoprotein F as an example

LC-MS and immunoassay can detect protein biomarkers. Immunoassays are more commonly used but can potentially be outperformed by LC-MS. These techniques have limitations including the necessity to generate separate calibration curves for each biomarker. We present a rapid mass spectrometry-based ass...

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Bibliographic Details
Main Authors: Kumar, A, Gangadharan, B, Cobbold, J, Thursz, M, Zitzmann, N
Other Authors: Wuhrer, M
Format: Journal article
Language:English
Published: Nature Publishing Group 2017