The interplay between membrane topology and mechanical forces in regulating T cell receptor activity

T cells are critically important for host defense against infections. T cell activation is specific because signal initiation requires T cell receptor (TCR) recognition of foreign antigen peptides presented by major histocompatibility complexes (pMHC) on antigen presenting cells (APCs). Recent advan...

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Bibliographic Details
Main Authors: Al-Aghbar, MA, Jainarayanan, AK, Dustin, ML, Roffler, SR
Format: Journal article
Language:English
Published: Springer Nature 2022