The interplay between membrane topology and mechanical forces in regulating T cell receptor activity
T cells are critically important for host defense against infections. T cell activation is specific because signal initiation requires T cell receptor (TCR) recognition of foreign antigen peptides presented by major histocompatibility complexes (pMHC) on antigen presenting cells (APCs). Recent advan...
Main Authors: | , , , |
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Format: | Journal article |
Language: | English |
Published: |
Springer Nature
2022
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