HPV8 field cancerization in a transgenic mouse model Is due to Lrig1+ keratinocyte stem cell expansion

β-Human papillomaviruses (HPVs) cause near ubiquitous latent skin infection within long-lived hair follicle (HF) keratinocyte stem cells. In patients with epidermodysplasia verruciformis, β-HPV viral replication is associated with skin keratosis and cutaneous squamous cell carcinoma. To determine th...

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Bibliographic Details
Main Authors: Lanfredini, S, Olivero, C, Borgogna, C, Calati, F, Powell, K, Davies, K, De Andrea, M, Harries, S, Tang, H, Pfister, H, Gariglio, M, Patel, G
Format: Journal article
Language:English
Published: Elsevier 2017