Re-engineering Caenorhabditis elegans SAS-6: from spirals to rings
<p>Centrioles have conserved 9-fold symmetry. This symmetry is templated by a scaffold of SAS-6. SAS-6 oligomerises to form a stack of rings, each with 9-fold radial symmetry, that forms the cartwheel, which imparts symmetry to the organelle. However, crystallographic and electron microscopy s...
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2019
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