Cork-in-bottle occlusion of fluoride ion channels by crystallization chaperones

Crystallization of dual-topology fluoride (Fluc) channels requires small, soluble crystallization chaperones known as monobodies, which act as primary crystal lattice contacts. Previous structures of Flucs have been solved in the presence of monobodies that inhibit fluoride currents in single-channe...

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Autori principali: McIlwain, B, Newstead, S, Stockbridge, R
Natura: Journal article
Lingua:English
Pubblicazione: Cell Press 2018