Induction of cell cycle and NK cell responses by live-attenuated oral vaccines against typhoid fever

The mechanisms by which oral, live-attenuated vaccines protect against typhoid fever are poorly understood. Here, we analyze transcriptional responses after vaccination with Ty21a or vaccine candidate, M01ZH09. Alterations in response profiles were related to vaccine-induced immune responses and sub...

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Bibliographic Details
Main Authors: Blohmke, CJ, Hill, J, Darton, TC, Carvalho-Burger, M, Eustace, A, Jones, C, Schreiber, F, Goodier, MR, Dougan, G, Nakaya, HI, Pollard, AJ
Format: Journal article
Published: Frontiers Media 2017