Characterizing the cellular immune response to subretinal AAV gene therapy in the murine retina

Although adeno-associated viral (AAV) vector-mediated retinal gene therapies have demonstrated efficacy, the mechanisms underlying dose-dependent retinal inflammation remain poorly understood. Here we present a quantitative analysis of cellular immune response to subretinal AAV gene therapy in mice...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Chandler, LC, McClements, ME, Yusuf, IH, Martinez-Fernandez de la Camara, C, MacLaren, RE, Xue, K
التنسيق: Journal article
اللغة:English
منشور في: Cell Press 2021