Characterizing the cellular immune response to subretinal AAV gene therapy in the murine retina

Although adeno-associated viral (AAV) vector-mediated retinal gene therapies have demonstrated efficacy, the mechanisms underlying dose-dependent retinal inflammation remain poorly understood. Here we present a quantitative analysis of cellular immune response to subretinal AAV gene therapy in mice...

詳細記述

書誌詳細
主要な著者: Chandler, LC, McClements, ME, Yusuf, IH, Martinez-Fernandez de la Camara, C, MacLaren, RE, Xue, K
フォーマット: Journal article
言語:English
出版事項: Cell Press 2021